Molecular Formula: C15H26O
CAS No: 23089-26-1
Purity≥98%
(-)-α-Bisabolol, mainly derived from chamomile, is utilized in cosmetic and personal care formulations.
In addition to its applications in cosmetics and personal care, (-)-α-Bisabolol possesses noteworthy research and development potential in the pharmaceutical sector due to its abundant bioactivity. The natural form of (-)-α-Bisabolol demonstrates enhanced bioactivity when compared to its synthetic versions.
| Product Name | CAS Number | Molecular Formula | Purity | Application |
| (-)-α-Bisabolol | 23089-26-1 | C15H26O | ≥98% | Personal Care/ Cosmetic/ Oral care |
Aromatic Soothing, Skin Protection
(-)-α-Bisabolol, primarily sourced from chamomile, is used in cosmetics and personal care products.
Rich Market Value
Apart from its use in cosmetics and personal care, (-)-α-Bisabolol holds significant research and development value in the pharmaceutical industry due to its rich bioactivity. The natural configuration of (-)-α-Bisabolol exhibits superior bioactivity compared to its chemically synthesized counterparts, which is highly desirable for wholesale cosmetic ingredients sourcing.
Microbial Total Synthesis of α-Bisabolol
The(-)-α-Bisabolol available in the market is generally a racemic mixture produced chemically. Hesheng Technology, integrating its proprietary (-)-α-Bisabolol microbial synthesis, significantly reduces production costs compared to chemical synthesis. This process also yields the more active single isomer, (-)-α-Bisabolol.
In the global cosmetic and pharmaceutical markets, not all bisabolol is created equal. While many suppliers offer chemically synthesized racemic mixtures, Hesheng Biotech utilizes cutting-edge microbial total synthesis to produce the highly bioactive single isomer.
Below is a technical comparison highlighting the superior performance of our product:
| Technical Feature | Hesheng (-)-α-Bisabolol | Common Synthetic Bisabolol |
| Production Process | Microbial Total Synthesis (Identical to natural chamomile) | Conventional Chemical Synthesis |
| Isomer Configuration | Pure Single Isomer: (-)-α-Bisabolol | Racemic Mixture (±) Mixture |
| Biological Activity | 2x Higher efficacy in soothing & anti-inflammation | Standard/Lower biological response |
| Chemical Purity | Ultra-high Purity ≥98% | Typically 85% - 95% (Varies) |
| Olfactory Profile | Clean, faint floral, and woody scent | May contain chemical solvent odors |
| Environmental Impact | Sustainable & Eco-friendly (Low carbon footprint) | High energy consumption & chemical waste |
| Supply Stability | Stable, bio-based fermentation (Not seasonal) | Subject to chemical raw material fluctuations |
Our microbial synthesis technology allows us to provide a natural-identical (-)-α-bisabolol that mirrors the molecular structure of chamomile extract but at a more competitive wholesale price. For formulators looking for high-potency anti-irritant ingredients, our single-isomer bisabolol offers double the skin-soothing performance compared to standard synthetic options.
The superior bioactivity of our microbial-synthesized (-)-α-Bisabolol (CAS 23089-26-1) makes it a premium choice for high-end formulations across multiple industries:
1. Anti-irritant & Sensitive Skincare
As a natural-identical soothing agent, (-)-α-Bisabolol is 2x more effective than synthetic versions in reducing skin redness and irritation.
Ideal for: Sensitive skin creams, post-sun repair lotions, anti-aging serums, and baby care products.
Key Benefit: Enhances the skin's healing process and provides a calming effect, making it a "gold standard" anti-irritant ingredient.
2. Professional & Clinical Oral Care
Leveraging its natural antibacterial and anti-inflammatory properties, our 98% purity bisabolol is optimized for advanced oral hygiene solutions.
Ideal for: Premium whitening toothpaste, therapeutic mouthwash, and gum protection gels.
Key Benefit: Helps reduce gingival inflammation and promotes overall gum health without the harsh side effects of synthetic chemicals.
3. Pharmaceutical Grade R&D
The high-purity single isomer structure of our (-)-α-Bisabolol offers consistent results for medical research and topical treatments.
Ideal for: Topical anti-inflammatory ointments, dermatological prescriptions, and pharmaceutical-grade skincare (Cosmeceuticals).
Key Benefit: Its high bioavailability and purity make it an excellent active pharmaceutical ingredient (API) for research into skin barrier repair and inflammatory response.
4. Daily Chemical & Personal Care
Beyond specialized treatments, it serves as a high-performance fragrance fixative and skin conditioner.
Ideal for: After-shave balms, deodorants, lip balms, and high-end shampoos.
Key Benefit: Provides a subtle, clean floral-woody scent while protecting the skin from daily environmental stressors.
The primary difference lies in the molecular configuration and biological potency. Natural-identical (-)-α-Bisabolol is a single active isomer, whereas synthetic bisabolol is typically a racemic mixture (±) containing only 50% of the active form. Our advanced microbial synthesis yields the 100% active (-)-alpha isomer, providing double the anti-inflammatory and skin-soothing efficacy compared to standard synthetic versions.
Our product is a high-purity active ingredient with a guaranteed purity of ≥98%. The specific CAS Number is 23089-26-1, identifying the pure (-)-alpha enantiomer. This ultra-high purity level ensures zero irritation from chemical by-products, making it suitable for high-end cosmeceuticals and sensitive skin formulations.
While our product is chemically and biologically identical to the bisabolol found in premium chamomile, it is produced via proprietary microbial total synthesis. This "lab-to-market" bio-manufacturing process offers three major advantages for B2B clients:
Sustainability: No land-intensive plant extraction required.
Supply Stability: Not affected by seasonal crop failures or weather.
Cost Efficiency: Significantly reduces production costs compared to traditional extraction while maintaining a Natural-Identical status.
Absolutely. Because our (-)-α-Bisabolol is produced through fermentation and microbial synthesis without the use of animal-derived precursors or harsh chemical catalysts, it perfectly aligns with Vegan, Cruelty-Free, and Clean Beauty industry standards.
At Hesheng Technology, we specialize in synthetic biology and innovative natural product manufacturing. We offer advanced raw material solutions and welcome collaboration opportunities!
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