Molecular Formula：C15H24
CAS No：17627-44-0/495-61-4/495-62-5
Constitutional formula: α-Bisabolene/β-Bisabolene/γ-Bisabolene
Bisabolene, a popular sesquiterpene flavor compound, primarily consists of three isomers: α, β, and γ, which are naturally found in the traditional aromatic plant myrrh. This compound can also be obtained from myrrh oil as well as from other natural essential oils, including ylang-ylang oil and cedar oil. The scent of bisabolene features a clean, fresh woody aroma, enriched by a rich fatty fragrance, and includes subtle floral and green notes, which blend seamlessly with natural myrrh essential oil.
Quick Facts: Bisabolene Technical Profile
CAS Numbers: 17627-44-0 (General), 495-61-4 (α), 495-62-5 (β).
Odor Profile: Clean, fresh woody, floral, and slightly green.
Production Method: Advanced Microbial Fermentation (Sustainable & Stable).
Purity: Platinum-grade ≥95%.
Primary Benefits: Anti-inflammatory, Anti-microbial, and Neuro-soothing.
As a leader in biosynthetic terpene technology, HeshengTech provides a comprehensive portfolio of high-purity sesquiterpenes. Bisabolene is a core component of our technical matrix, which includes other high-performance compounds such as Beta-Caryophyllene for woody aromatic depth and Farnesene for advanced emollient formulations. Our integration of AI-driven metabolic engineering ensures that every sesquiterpene we produce meets the 'Platinum Standard' for purity and sustainability.
| Product Name | CAS Number | Molecular Formula | Purity | Application |
| Bisabolene | C15H24 | 17627-44-0/ 495-61-4/ 495-62-5 | ≥95% | Flavors & Fragrances、 Pharmaceutical Applications、 Personal care ingredient |
The Precious Aroma of Myrrh
Bisabolene, as a favored sesquiterpene flavor compound, mainly has three isomers: α, β, and γ, which naturally exist in the traditional aromatic plant myrrh. Bisabolene can also be extracted from myrrh oil and other natural essential oils such as ylang-ylang oil and cedar oil. The aroma of bisabolene contains a clean and fresh woody scent, with a rich fatty aroma, complemented by a light floral and green note, which harmonizes well with natural myrrh essential oil.
Anti-Inflammatory and Soothing, Calming the Nerves
Bisabolene also has potential biological activity. Currently, Bisabolene is being studied as an anti-inflammatory and anti-cancer agent, β-Bisabolene and γ-Bisabolene have highly calming and soothing effects on the skin, anti-inflammatory and anti-sensitivity, nourishing the nervous system, and balancing endocrine functions.
Biosynthesis of Bisabolene
Wuhan Hesheng Technology utilizes synthetic biology strategies to innovatively develop a synthetic route for Bisabolene. With the support of high-throughput automation platforms and AI technology platform, the yield of Bisabolene production strains has been significantly improved and optimized. The Bisabolene produced by Wuhan Hesheng Technology has stable production capacity and is environmentally friendly.
Flavors & Fragrances
Pharmaceutical Applications
Personal care ingredient
Chemically, they are identical as both consist of the C15H24 molecular structure. However, biosynthetic Bisabolene from HeshengTech offers three critical advantages for industrial formulators:
Purity: Achieves a platinum-level consistency of ≥95%, free from the agricultural residues (pesticides) found in myrrh or ylang-ylang extracts.
Isomer Control: Precise control over α, β, and γ isomers.
Supply Chain Stability: It is decoupled from seasonal harvest volatility, ensuring a stable, year-round price for large-scale manufacturing.
Yes. Due to its well-documented bioactivity, our high-purity Bisabolene is increasingly utilized in pharmaceutical R&D. Studies highlight its potential as an anti-inflammatory and anti-cancer agent. Its high lipophilicity also makes it an excellent starting material or carrier in therapeutic development, particularly for drug delivery systems targeting inflammatory pathways.
Absolutely. The β and γ isomers produced via our biosynthetic fermentation are specifically known for their potent calming and anti-sensitizing effects on the skin barrier. Because our process is vegan, non-GMO, and solvent-free, it perfectly aligns with the "Clean Beauty" and ESG (Environmental, Social, and Governance) standards required by top-tier cosmetic brands in 2026.
Bisabolene acts as a versatile sesquiterpene flavor compound. It provides a clean, fresh woody aroma with subtle floral and green undertones. It is particularly effective when used as a base note to harmonize and fix natural myrrh or cedarwood scents, extending the longevity of the fragrance profile without adding synthetic "off-notes."
At Hesheng Technology, we specialize in synthetic biology and innovative natural product manufacturing. We offer advanced raw material solutions and welcome collaboration opportunities!
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